Journal of Biological Research and Biotechnology


Bio-Research is a multidisciplinary biological and biotechnology journal published by the Faculty of Biological Sciences, University of Nigeria, Nsukka. We publish scientific reports on biological and biotechnology subjects in the form of original articles, reviews brief reports, and case reports.

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Current Publications

Chitosan-based nanoparticles sustenance and potentiation of the antibacterial effect of ampicillin against drug resistance among strains of Escherich…

The study seeks to evaluate nanoparticles based on chitosan for enhanced delivery of ampicillin in plasmid-mediated drug resistance. Serial dilutions of a mixed population of E. coli was plated on nu…

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  Onuigbo EB, Anozie-Ikeanyi C,…   Vol.18  No.2 - 2020

Antimicrobial activity of the crude extracts of Parkia biglobosa (Jacq) seeds on selected clinical isolates

Parkia biglobosa (Jacq) is a wild leguminous plant found in North-Central zone of Nigeria with high calorific value, essential proteins, fatty acids, and vitamins. The study investigated the antimicr…

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  Ajiboye AE and Hammed BA   Vol.18  No.2 - 2020

Antibacterial screening of Phoenix dactylifera L. (Date palm) seed extracts on some bacterial isolates associated with dental caries

Dental diseases refer to conditions of deterioration and disintegration of the oral cavity due to the activities of pathogenic microbes. This study was carried out to determine the antibacterial acti…

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  Adedayo MR, Ajiboye AE and Ad…   Vol.18  No.2 - 2020

Effect of a co-processed excipient on the disintegration and drug release profile of ibuprofen tablets

Tablets at present, remain the most preferred oral dosage form because of many advantages they offer to formulators as well as physicians and patients. The objective of this work was to determine the…

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  Mohammed BB,John EJ and Ajuji…   Vol.18  No.1 - 2020

Checklist and Comparison of Butterfly Species found in Zoological and Botanical Gardens, University of Nigeria, Nsukka, Enugu State, Nigeria

Butterflies are creatures of nature with great economic importance as pollinators and bio-indicators. This study provides checklist of butterfly species present in Zoological and Botanical gardens of…

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  D Echude, MI Amobi, SU Umar, …   Vol.18  No.1 - 2020

Inhibition of dehydrogenase activity in S. typhimurium by ethanolic and methanolic extracts of Carica papaya and Ocimum gratissimum

Dehydrogenase and inhibitions of dehydrogenase activities in Salmonella typhimurium by ethanolic and methanolic leaf extracts of Ocimum gratissimum and Carica papaya were investigated. Dehydrogenase …

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  SI Umeh , IP Umunna, JU Udensi   Vol.18  No.1 - 2020

Evaluation of some organic substrates for the growth and yield of oyster mushroom Pleurotus ostreatus (Jacq.Fr.) Kumm in southeast Nigeria OC Josepha…

Four organic substrates; Mahogany Sawdust (MSD), Corn Cobs (CC), Oil Palm Fruit Fibre (OPFF) and Rice Bran (RB) were evaluated for their effects on growth and yield of Pleurotus ostreatus (Jacq.Fr.) …

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  OC Josephat, CC Onyeke, NV Ch…   Vol.18  No.1 - 2020

A preliminary study on the antimicrobial activities and gas chromatography-mass spectrometry (GC-MS) analysis of the ethyl acetate extract of Dennett…

The study investigated the antimicrobial properties and the chemical composition of ethyl acetate extract of Dennettia tripetala (pepper fruit) seeds. Crude extract obtained by maceration of pulveriz…

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  UF Babaiwa, SO Eraga, EO Ojug…   Vol.18  No.1 - 2020

Antimicrobial and time-kill kinetics of the aqueous extract of Citrullus lanatus (Thunb.) seeds

This study evaluated the antimicrobial property of the aqueous extract of Citrullus lanatus (watermelon) seeds and its concentration-effect relationship (time-kill studies) on typed bacterial and fun…

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  UF Babaiwa, SO Eraga, JO Aker…   Vol.18  No.1 - 2020

The efficacy of aqueous leaf extracts of Hyptis suaveolens (L.) Poit and Ocimum basilicum (L.) in the control of Meloidogyne spp infecting Onion, All…

The efficacy of aqueous leaf extracts of Hyptis suaveolens and Ocimum basilicum in the control of Meloidogyne spp infecting Allium cepa L (Onion) was investigated using sterile soil that was filled i…

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  OB Okechalu, ND Zwalnan, OA A…   Vol.18  No.1 - 2020

Preliminary studies on the antifungal activities of ethanol and hot water extracts of local spices against fluconazole-resistant Candida albicans iso…

This study evaluated the antifungal effect of local spices namely Capsicum annum var. shombo, Capsicum annuum var. atarugu, Capsicum annuum var. Nsukka yellow pepper, Zingiber officinale and Allium s…

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  C.L. Akaihe, P.E. Chidebelu, …   Vol.17  No.1 - 2019

Changes in catalase activities during malting of some improved Nigerian sorghum grain varieties

The catalase activities of ten germinating improved sorghum varieties were monitored over a 4-day period to determine the effect of malting on them. This was done using standard methods that involved…

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  C.I. Nnamchi, B.N. Okolo, A.N…   Vol.17  No.1 - 2019