Use of dika fat in the formulation of sustained release theophylline tablets and capsules

Sustained release theophylline tablets and capsules were prepared with dika fat, a solid vegetable oil extracted from the kernels of Irvingia gabonesis var gabonesis and var excelsia. Anhydrous theophylline was incorporated into dika f…

  GC Umekoli, JO Onyechi, OK Udeala

 Vol.7  No.1 - 2009
Status:  Published

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Anti-ulcer activity of the leaf extracts of Borreria ocymoides in rats

The anti-ulcer properties of the leaf extracts of Borreria ocymoides Burm. F. (Rubiaceae) was investigated. Sixty (60) albino rats of either sex weighing 160-216g and fifteen (15) albino mice weighing 25-36 g were used for the study. S…

  CN Okwuosa, DC Nwachukwu, PUO Achukwu, CG Ezeorah, AA Eze

 Vol.7  No.1 - 2009
Status:  Published

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Effects of phenobarbital administration on the histology of the liver and brain, and the activities of some biochemical parameters of the liver of Wister rats

The effects of phenobarbital on the histology of the liver and the brain and on selected biochemical parameters of the liver of wistar rats were studied. Histological examination showed prominent lesions in the liver and brain of the t…

  AA Eze, DC Nwaohukwu, PU Achukwu, CN Okwuosa

 Vol.7  No.1 - 2009
Status:  Published

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In-Vitro antibacterial activity of bioactive plant extracts against methicillin-resistant strains of staphylococcus aureus

Methanol extract of leaves of five different Nigerian plants were tested for activity against three drug resistant strains of Staphylococcus aureus by the agar well diffusion and broth microdilution techniques. The S. aureus strains we…

  EA Eze, CO Nwuche, AM Ugwu

 Vol.7  No.1 - 2009
Status:  Published

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 Vol.7  No.1 - 2009
Status:  Published

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Co-infection and morphometrics of three clinostomatids (Digenea: Clinostomatidae) in Tilapia guinensis Bleeker, 1862 from Opi lake, Nigeria

Co-infection and morphometrics of helminth parasites of Tilapia guinensis in Opi Lake (GPS N06.75275*, E007.49104*), were studied from (Nov 2007– Oct 2008) using multiple fishing gear techniques; cast nets, hook and line, and seine net…

  PC Echi, FC Okafor, JE Eyo

 Vol.7  No.1 - 2009
Status:  Published

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The effect of cosolvents and surfactants on the aqueous solubility of Irbesartan

It was considered an interest to enhance the aqueous solubility of irbesartan. To accomplish this objective, the solubilization of irbesartan by cosolvency and micellization was investigated. It was found that all the cosolvents (ethan…

  CJ Mbah, CM Eneasato

 Vol.7  No.1 - 2009
Status:  Published

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A study of the potential interaction of valsartan with some electrolytes

The effect of electrolytes (salts) on the partition coefficient of valsartan was studied at room temperature. The investigation was done by partitioning valsartan between 1-octanol and electrolyte solutions of varying concentrations. I…

  CJ Mbah

 Vol.7  No.1 - 2009
Status:  Published

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Evaluation of anti-diarrhoeal action of a hot-water infusion of ocimum gratissimum, linn

Hot-water infusion of the leaf of Ocimum gratissimum was tested for anti-diarrhoeal action using animal models. Protection of the animals from castor oil-induced diarrhoea and reduction of the number and frequency of faecal output were…

  VC Okore, CI Asogwa, PO Nnamani

 Vol.7  No.1 - 2009
Status:  Published

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Quantitative difference method for estimation of fertilizer nitrogen balance and uptake by zea mays on an orthic oxisol of North Central Nigeria

The percentic recovery and balance of fertilizer nitrogen can be determined by different methods. In this study, quantitative difference method in recovery of Nitrogen of above-ground dry matter was applied to investigate the uptake of…

  PI Ezeaku

 Vol.7  No.1 - 2009
Status:  Published

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