In Vitro Study of Release of Metronidazole Tablets Prepared from Okra Gum, Gelatin Gum and their Admixture


The aim of this study is to evaluate the ability of okra gum to release it\'s medicament in bioadhesive polymer-based drug delivery system. Bioadhesive studies using the tensiometer were done to evaluate its bioadhesivenes. Conventional tablets were made with okra gum as binder and in-vitro release studies carried out using gelatin as a standard reference. Okra gum was seen to have a comparable result with gelatin in term of the bioadhesive property the amount of drug released. Keywords: Bioadhesive, Okra gum, Gelatin gum, Metronidazole, Release studies Bio-Research Vol. 6 (1) 2008: pp. 339-342

 MA Momoh, MU Akikwu, JI Ogbona, UE Nwachi

 

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